Sandwich Student - Biology Lab - Method Developer - Placement

The Science and Technology Facilities Council (STFC)
09 Oct 2018
06 Nov 2018
Start Date
The Science and Technology Facilities Council (STFC) is one of Europe's largest research organisations. We're trusted to support, enable and undertake pioneering projects in an amazing diversity of fields. Through world-class facilities and people, we're driving ground-breaking advances in science, technology and Engineering.

STFC is one of nine organisations that have been brought together to create UK Research and Innovation (UKRI); a new organisation with a vision to ensure the UK maintains its world-leading position in research and innovation.

Each year we offer opportunities to undergraduate sandwich students to gain practical experience, working alongside technical experts at the forefront of scientific research. We offer an invaluable experience with exposure to world class science and technology, and the opportunity to develop working relationships that continue well after your placement has finished.

ISIS is a world leading centre in physical and life science research using neutrons and muons as scientific tools. This position will be based in ISIS biology laboratory, part of ISIS support laboratories group. ISIS biology laboratories have a wide range of equipment to help beam time users to prepare their samples for beam time.

You will have an opportunity to work in our bio lab, mainly in commissioning a bio fermenter, used to grow bacteria under optimised conditions. They will be working to support the users in preparing their samples and hence optimising the growth conditions of various species of bacteria to increase the protein yield. There will be plenty of opportunities for you to learn molecular cloning and genetic modification techniques widely used in biological research areas. This will give you a chance to work closely with the ISIS Large Scale Structure group (LSS).

Protein characterisation and purification -For successful SANS and NR experiments on biological molecules (proteins, polypeptides and nucleic acids) the sample purity, homogeneity and solubility have to be extensively optimized before the experiment. You will characterise the protein homogeneity under the conditions that will be used for neutron experiments using biophysical techniques such as SDS-PAGE, size-exclusion chromatography, circular dichroism, analytical ultracentrifugation, dynamic light scattering, multi-angle static light scattering.

  • to develop method for using Bio fermenter for fed batch and continuous batch with various bacterial species
  • to prepare documentation for the above procedures
  • to support ISIS users in sample preparation and characterisation.

Knowledge, Skills and Experience

Shortlisting (S) and Interview (I) Criteria

  • at university, enrolled on an undergraduate degree course and required or have requested to take a year out of studies to gain experience within industry (S)
  • right to live and work in the UK (S)

  • grade A in Biology, Maths and Chemistry in A levels.
  • understanding of Molecular Biology (S&I)

Knowledge, Skills and Experience

  • basic biology knowledge and understanding of bacterial growth dynamics. (S&I)
  • biology Lab experience

  • lab experience
  • knowledge of aseptic techniques
  • understanding of BIOCOSHH and Genetic modifications
  • knowledge of aseptic techniques
  • molecular cloning
  • ability to write scientific experimental reports

Personal Skills, Qualities and Attributes (I)

  • ability to work in a team and problem solving skills
  • ability to prioritise work load
  • good presentation skills
  • good communication skills

Special Requirements

  • comfortable to be working in radiation and controlled area
  • willingness to work with Class 1 and class 2 pathogens.

Organization Description

UK Research and Innovation is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, and a vision to ensure the UK maintains its world-leading position in research and innovation. More information can be found at .

The Science and Technology Facilities Council is a world-leading multi-disciplinary science organisation, and our goal is to deliver economic, societal, scientific and international benefits to the UK and its people - and more broadly to the world.

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